CRISPR
-
By silencing the gene responsible for regulating ‘bad’ cholesterol without altering the primary DNA sequence, researchers have unlocked the potential of epigenetic editing to safely and effectively treat not just this but a wide range of diseases.
-
The FDA has approved the first cell-based gene therapies for treating sickle cell disease, one of which is the first approved therapy to utilize the CRISPR/Cas9 gene editing technology. It signals advancements in gene therapy and regenerative medicine.
-
A new study has identified, for the first time, how the mutated protein p53, present in half of all human cancers, drives tumor growth. The discovery will not only facilitate a rethink of the way cancer is treated but may lead to new therapeutics.
-
CRISPR systems are powerful tools for genetic engineering, but they have their limitations. Now, scientists have discovered almost 200 new CRISPR systems in bacteria, and found that some can edit human cells even more precisely than existing ones.
-
The term ‘personalized medicine’ is being used more and more frequently. But what does it mean? This explainer outlines what personalized medicine is, its advantages and some concerns that have been raised in relation to it.
-
Researchers presented the interim results of a clinical trial using a single infusion of gene-editing technology to permanently switch off LDL cholesterol production in people with a genetic condition that elevates levels of the ‘bad’ cholesterol.
-
Following on from the discovery of programmable DNA-cutting enzymes Fanzors, scientists have identified more than 3,600 Fanzors in a broad set of species. It presents a massive opportunity in the development of new medicines, gene therapy and biotech.
-
Splitting the gene editor used in traditional CRISPR technology creates a more precise tool with significantly less chance of causing unintended mutations, a new study has found. The novel tool could correct half of the mutations that cause disease.
-
For the first time, scientists have successfully produced full-length spider silk fibers using genetically modified silkworms. This silk has the potential to provide a scalable, sustainable and better-quality alternative to current synthetic fibers.
-
Conventional breeding of trees takes time, but CRISPR gene editing should help speed things up. Now, scientists at North Carolina State University have used CRISPR to adjust the genomes of poplar trees to make them easier to turn into paper products.
-
Yale scientists have discovered a new potential treatment avenue to fight cancer. Using CRISPR gene-editing, the team eliminated extra chromosomes from cancer cells and found that they could no longer grow out of control.
-
CRISPR-Cas9 is the household name of genetic engineering tools, but there might be other, better ways. MIT scientists have now demonstrated an alternative called Fanzor, which is naturally found in animals so could be a better fit for human use.
Load More