 Life Science Events, Jobs, Directory, News Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight into how cancer and immune cells interact within the tumor microenvironment.
Beginning in the 20th century, techniques such as immunohistochemistry and in situ hybridization allowed researchers to localize proteins and nucleic acid sequences directly in tissue samples. However, these analyses were typically limited to a single marker at a time. More recently, advances in high-throughput sequencing and mass spectrometry enable the simultaneous analysis of hundreds, or even thousands, of molecules while preserving spatial context. To explore the future of spatial biology, we spoke with four companies pioneering these technologies.
Spatial transcriptomics
The transcriptome is the complete collection of RNA produced in a cell or tissue at a given time. It reflects active gene expression, which varies with disease state…
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