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USA TODAY Sports' Week 4 NFL picks

USA TODAY Sports

Week 4 of the NFL season kicks off Thursday with the league's longest-running rivalry as the Chicago Bears and Green Bay Packers meet for the 193rd time in the regular season.

Broncos QB Trevor Siemian will have to overcome Raiders DE Khalil Mack (52) if Denver is to improve to 3-0 at home this season.

Sunday's action features the second game of the year in London, where the Miami Dolphins will "host" the New Orleans Saints at Wembley Stadium with a 9:30 a.m. ET kickoff.

Elsewhere, the Atlanta Falcons and Kansas City Chiefs will try to remain perfect by going 4-0.

PHOTOS: Power rankings heading into Week 4

 

NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.

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